Persistent intrathecal secretion of oligoclonal, Borrelia burgdorferi -specific IgG in chronic meningoradiculomyelitis
Identifieur interne : 001535 ( Main/Exploration ); précédent : 001534; suivant : 001536Persistent intrathecal secretion of oligoclonal, Borrelia burgdorferi -specific IgG in chronic meningoradiculomyelitis
Auteurs : R. Martin [Allemagne] ; U. Martens [Allemagne] ; V. Sticht-Groh [Allemagne] ; R. Dörries [Allemagne] ; H. Krüger [Allemagne]Source :
- Journal of Neurology [ 0340-5354 ] ; 1988-03-01.
English descriptors
- KwdEn :
- Teeft :
- Aetiological agent, Antigen specificity, Borrelia, Borrelia burgdorferi, Burgdorferi, Burgdorferi antigen, Cerebrospinal fluid, Chronic lymphomeningoradiculitis, Chronic meningoradiculomyelitis, Chronic stage, Clin microbiol, Clinical symptoms, Corresponding immunoblot, Disease activity, Distribution pattern, Erythema chronicum migrans, Filter paper, Further step, Immunoblot, Immunoblot analysis, Immunoblot technique, Immunoblotting procedure, Immunofluorescence test, Immunoglobulin, Intrathecal, Intrathecal production, Intrathecal synthesis, Isoelectric point, Kind gift, Laboratory findings, Lyme, Lyme disease, Lymphocytic meningoradiculitis, Lymphocytic meningoradiculitis syndrome, Meningoradiculitis, Multiple sclerosis, Mumps meningitis, Neurol, Nitrocellulose filters, Normal values, Oligoclonal, Oligoclonal bands, Peripheral blood, Persistent secretion, Radicular pain, Radiculomyelitis, Specific antibodies, Total protein, Tuberculous meningitis, Varicella zoster meningoencephalitis, Weak bands.
Abstract
Summary: In the cerebrospinal fluid IgG of five patients with lymphomeningoradiculitis (Bannwarth's syndrome) and radiculomyelitis studied by immunoblot technique an oligoclonal pattern was found. Most of these oligoclonal bands were specific for Borrelia burgdorferi. In patients suffering from chronic meningoradiculomyelitis, repeated CSF examination by this technique showed persistent secretion of identical IgG bands. Thus, the specific humoral immune response and the disease activity could be documented over the course of the disease.
Url:
DOI: 10.1007/BF00314352
Affiliations:
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Krüger</name><affiliation wicri:level="4"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Abteilung Neurologie, Universität Würzburg, D-8700, Würzburg</wicri:regionArea><orgName type="university">Université de Wurtzbourg</orgName><placeName><settlement type="city">Wurtzbourg</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Basse-Franconie</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Neurology</title><title level="j" type="abbrev">J Neurol</title><idno type="ISSN">0340-5354</idno><idno type="eISSN">1432-1459</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><date type="published" when="1988-03-01">1988-03-01</date><biblScope unit="volume">235</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="229">229</biblScope><biblScope unit="page" to="233">233</biblScope></imprint><idno type="ISSN">0340-5354</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0340-5354</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Borrelia burgdorferi</term><term>Cerebrospinal fluid</term><term>Immunoblot technique</term><term>Lyme disease</term><term>Lymphomeningoradiculitis</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Aetiological agent</term><term>Antigen specificity</term><term>Borrelia</term><term>Borrelia burgdorferi</term><term>Burgdorferi</term><term>Burgdorferi antigen</term><term>Cerebrospinal fluid</term><term>Chronic lymphomeningoradiculitis</term><term>Chronic meningoradiculomyelitis</term><term>Chronic stage</term><term>Clin microbiol</term><term>Clinical symptoms</term><term>Corresponding immunoblot</term><term>Disease activity</term><term>Distribution pattern</term><term>Erythema chronicum migrans</term><term>Filter paper</term><term>Further step</term><term>Immunoblot</term><term>Immunoblot analysis</term><term>Immunoblot technique</term><term>Immunoblotting procedure</term><term>Immunofluorescence test</term><term>Immunoglobulin</term><term>Intrathecal</term><term>Intrathecal production</term><term>Intrathecal synthesis</term><term>Isoelectric point</term><term>Kind gift</term><term>Laboratory findings</term><term>Lyme</term><term>Lyme disease</term><term>Lymphocytic meningoradiculitis</term><term>Lymphocytic meningoradiculitis syndrome</term><term>Meningoradiculitis</term><term>Multiple sclerosis</term><term>Mumps meningitis</term><term>Neurol</term><term>Nitrocellulose filters</term><term>Normal values</term><term>Oligoclonal</term><term>Oligoclonal bands</term><term>Peripheral blood</term><term>Persistent secretion</term><term>Radicular pain</term><term>Radiculomyelitis</term><term>Specific antibodies</term><term>Total protein</term><term>Tuberculous meningitis</term><term>Varicella zoster meningoencephalitis</term><term>Weak bands</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary: In the cerebrospinal fluid IgG of five patients with lymphomeningoradiculitis (Bannwarth's syndrome) and radiculomyelitis studied by immunoblot technique an oligoclonal pattern was found. Most of these oligoclonal bands were specific for Borrelia burgdorferi. In patients suffering from chronic meningoradiculomyelitis, repeated CSF examination by this technique showed persistent secretion of identical IgG bands. Thus, the specific humoral immune response and the disease activity could be documented over the course of the disease.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Bavière</li><li>District de Basse-Franconie</li></region><settlement><li>Wurtzbourg</li></settlement><orgName><li>Université de Wurtzbourg</li></orgName></list><tree><country name="Allemagne"><region name="Bavière"><name sortKey="Martin, R" sort="Martin, R" uniqKey="Martin R" first="R." last="Martin">R. Martin</name></region><name sortKey="Dorries, R" sort="Dorries, R" uniqKey="Dorries R" first="R." last="Dörries">R. Dörries</name><name sortKey="Kruger, H" sort="Kruger, H" uniqKey="Kruger H" first="H." last="Krüger">H. Krüger</name><name sortKey="Martens, U" sort="Martens, U" uniqKey="Martens U" first="U." last="Martens">U. Martens</name><name sortKey="Sticht Groh, V" sort="Sticht Groh, V" uniqKey="Sticht Groh V" first="V." last="Sticht-Groh">V. Sticht-Groh</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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